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Articles & Links about ALDH2 Deficiency

Here is a helpful list of 3rd party articles discussing the seriousness of ALDH2 Deficiency and what it means for the community. Research on ALDH2 Deficiency and the health risks is abundant and the problem is very well known. Essential AD2 is the only product available that alleviates acetaldehyde exposure in those with ALDH2 Deficiency.



NBC News discusses how Alcohol Flush Reaction is a red flag for cancer risk, particularly esophageal cancer and is a major public health concern. These risks are due to an inability to metabolize acetaldehyde, the toxic carcinogen those with ALDH2 Deficiency can't metabolize.

NBC News: 'Asian Flush' red flag for risk of cancer


Asian Flush Reaction





The University of Southern California News discusses the risks of taking antihistamine products like Zantac or Pepcid to reduce Alcohol Flush Reaction. While very popular among younger individuals with ALDH2 Deficiency, use of antihistamines while drinking can have serious health consequences, and lead to dangerous levels of intoxication.

Antihistamines prevent 'Asian Flush' - alcohol induced facial redness - but pose risks


Antihistamines like Pepcid for Asian Flush





The National Cancer Institute identifies acetaldehyde as the primary toxin from alcohol that damages DNA and proteins in the body. Acetaldehyde creates free radicals, which damage DNA and can lead to cancer. Continued acetaldehyde exposure is also the cause of the damage to the liver that causes liver disease and cirrhosis.

Alcohol and Cancer Risk


Acetaldehyde Damages the Liver





This helpful overview of Acetaldehyde from Wikipedia details why acetaldehyde is so dangerous, its numerous sources, acetaldehyde as the most common air pollutant, and its carcinogenic properties. 

Acetaldehyde Sources of Exposure







Here is one of many published scientific studies describing the increased cancer risk for those with ALDH2 Deficiency due to continued exposure to acetaldehyde. These findings indicate that those with ALDH2 Deficiency are up to 70-times the risk for esophageal cancer.

The Alcohol Flush Response: An Unrecognized Risk Factor for Esophageal Cancer from Alcohol Consumption



Esophageal Cancer